Ру O’z Ўзб Eng
+998 71 228-06-96

+998 78 120-16-61

1002
not found
Кенгайтирилган қидирув
    Press-service

    News

    not found

    New asthma cause identified – and a new angle for treatment

    As common as asthma is, exactly how it starts remains murky. Scientists have now identified a new root cause, and importantly a new angle for treating the disease that can prevent the main symptoms. According to WHO, asthma affects around 262 million people worldwide, but despite its prevalence there’s still much scientists don’t understand about the condition. It’s usually treated as an inflammatory disease – triggers like pollen or dust set off inflammation that narrows the airways and makes it difficult to breathe. Inhaler medications can relieve this by relaxing the airways and calming inflammation. But the new study points to a different root cause, of which inflammation is itself a symptom. When the airway muscles contract – known as bronchoconstriction – the epithelial cells that line the airways are 'squeezed out' and later die. With fewer of these cells acting as a barrier, the chances for future asthma attacks increase. “As cell biologists who watch processes, we could see that the physical constriction of an asthma attack causes widespread destruction of the airway barrier,” said Professor Jody Rosenblatt, lead author of the study. “Without this barrier, asthma sufferers are far more likely to get long-term inflammation, wound healing, and infections that cause more attacks. By understanding this fundamental mechanism, we are now in a better position to prevent all these events.” The team made the discovery in mouse models, and importantly also found a potential way to prevent too much cell extrusion. The chemical compound gadolinium was previously found to block the process, and in the new study the researchers showed that it worked in mice to prevent cell damage and inflammation associated with asthma attacks. “Current therapies do not prevent this destruction – an inhaler such as Albuterol opens the airways, which is critical to breathing but, dishearteningly, we found it does not prevent the damage and the symptoms that follow an attack,” said Rosenblatt. “Fortunately, we found that we can use an inexpensive compound, gadolinium which is frequently used for MRI imaging, to stop the airway damage in mice models as well as the ensuing inflammation and mucus secretion. Preventing this damage could then prevent the build-up of musculature that cause future attacks.” Of course, mice aren’t humans, so there’s no guarantee that these results will necessarily carry across to humans. But the team says that the new study could help lead to new types of asthma therapies that aren’t just about treating symptoms. The research was published in the journal Science.

    • 1 May, 15:21
    • Read more
    not found

    AstraZeneca admits its Covid vaccine can cause rare side effect in court documents for first time

    AstraZeneca has admitted for the first time in court documents that its Covid vaccine can cause a rare side effect, in an apparent about-turn that could pave the way for a multi-million pound legal payout. The pharmaceutical giant is being sued in a class action over claims that its vaccine, developed with the University of Oxford, caused death and serious injury in dozens of cases. Lawyers argue the vaccine produced a side effect which has had a devastating effect on a small number of families. The first case was lodged last year by Jamie Scott, a father of two, who was left with a permanent brain injury after developing a blood clot and a bleed on the brain that has prevented him from working after he received the vaccine in April 2021. The hospital called his wife three times to tell her that her husband was going to die. AstraZeneca is contesting the claims but has accepted, in a legal document submitted to the High Court in February, that its Covid vaccine “can, in very rare cases, cause TTS”. TTS – which stands for Thrombosis with Thrombocytopenia Syndrome – causes people to have blood clots and a low blood platelet count. Fifty-one cases have been lodged in the High Court, with victims and grieving relatives seeking damages estimated to be worth up to £100 million. AstraZeneca’s admission – made in a legal defence to Mr Scott’s High Court claim – follows intense legal wrangling. It could lead to payouts if the drug firm accepts that the vaccine was the cause of serious illness and death in specific legal cases. The Government has pledged to underwrite AstraZeneca’s legal bills.

    • 1 May, 12:25
    • Read more
    not found

    The "Development strategy" center developed the symbol of "Uzbekistan — 2030" strategy

    The basis of the symbol of the "Uzbekistan - 2030" strategy is the image of the Independence Monument in the "New Uzbekistan" park of as a symbol of "New Uzbekistan" and the "Third Renaissance". If the Independence Monument reflected in the symbol is interpreted as an expression of the mutual harmony of our country's history, present day and future, its elevation embodies the unity and solidarity of our people, Uzbekistan's solidarity with the countries of the world, and peace-loving policy. Also, in the dynamics of upward lines, there are five priorities of the "Uzbekistan-2030" strategy and the noble idea of full and successful implementation of the 100 goals set in it. In the upper part of the logo there is a Humo bird, which is a symbol of happiness, freedom and peace. It is embodied as a symbol of an ancient state, that has more than three thousand years of statehood experience, and at the same time, young and blooming, that relies on its hard-working and noble people, with bubbling feelings of love of freedom in their blood, who have great dreams and goals. The pillars connected to Humo bird are depicted as the expression of human rights and freedoms, national and universal values, education and upbringing, state and society balance. Also, this element means compliance and harmony between the exercise of power by the state and the interests, freedoms, and demands of society. In the symbol of the strategy, a triangular shape element was used as a metaphoric symbol of the principle of "New Uzbekistan - a social state" defined as a rule in the newly revised Constitution of Uzbekistan. It is the cornerstone of fact that protection of all layers of the population, creation of equal opportunities for them, especially all-round support for families, children, women, the elderly, persons with disabilities, protection from unemployment, guaranteed quality education, qualified medical care are always the priority for the state during the period of active reforms. The society reflected in the interior of the Independence Monument is the image of one nation of Uzbekistan. It embodies our peaceful, hardworking, tolerant and wise people who have high human qualities and are united for a great goal. Also, this image reflects the fact that all the reforms implemented in the country are focused on the value of a person, his comfortable life, and it means that the priceless wealth of the state is the people. This element shows our nation's commitment to the ideals of equality, social justice and solidarity. At the same time, it means that a close-knit family, as the basic unit of society, is always under the protection of society and the state. Information Service, Development Strategy Center

    • 26 April, 12:00
    • Read more
    not found

    09:50 / 22.04.2024

    Next pandemic likely to be caused by flu virus, scientists warn

    not found

    08:50 / 19.04.2024

    WHO: Medical Product Alert N°1/2024: Falsified (contaminated) USP/EP PROPYLENE GLYCOL

    not found

    14:43 / 18.04.2024

    WHO sounds alarm on viral hepatitis infections claiming 3500 lives each day

    not found

    12:51 / 15.04.2024

    Nigeria becomes first country to roll out new meningitis vaccine, WHO says

    not found

    12:48 / 04.04.2024

    Study links e-cigarette use with higher risk of heart failure

    not found

    10:03 / 01.04.2024

    Human brains are getting larger

    Нажмите на кнопку ниже, чтобы прослушать текст Powered by GSpeech